V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

Summary: Antibodies that bind residue K169 in the V2 region of the HIV-1 envelope correlated with reduced risk of infection in the RV144 vaccine trial but were restricted to two ED-motif-encoding light chain genes.Here, we identify an HIV-infected donor with high-titer V2 peptide-binding antibodies and isolate two antibody lineages (CAP228-16H/19F

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CR-Mask RCNN: An Improved Mask RCNN Method for Airport Runway Detection and Segmentation in Remote Sensing Images

Airport runways, as the core part of airports, belong to vital national infrastructure, Low Power Schottky and the target detection and segmentation of airport runways in remote sensing images using deep learning methods have significant research value.Most of the existing airport target detection methods based on deep learning rely on horizontal b

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